文章基本信息

标题：Calmodulin activation of plant microsomal Ca2+ uptake
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作者：Peter Dieter ; Dieter Marmé
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1980
卷号：77
期号：12
页码：7311-7314
DOI：10.1073/pnas.77.12.7311
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The active ATP-dependent uptake of Ca2+ into a plasma membrane-enriched microsomal fraction from plants is stimulated by the addition of plant as well as bovine brain calmodulin. This stimulation occurs only when the microsomes are prepared in the presence of EDTA. Plant calmodulin also activates the bovine brain 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17 ). Mitochondrial Ca2+ accumulation is not affected by calmodulin. The calmodulin-mediated activation of microsomal Ca2+ uptake is abolished by the antipsychotic drug fluphenazine, whereas the calmodulin-independent Ca2+ uptake is only slightly decreased.
关键词：zucchini squash ; bovine brain ; 3′,5′-cyclic-nucleotide phosphodiesterase ; fluphenazine