文章基本信息

标题：Water permeability changes studied by 17O nuclear magnetic resonance during differentiation of Friend leukemia cells
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作者：N Haran ; Z Malik ; A Lapidot 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1979
卷号：76
期号：7
页码：3363-3366
DOI：10.1073/pnas.76.7.3363
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Water permeability of Friend leukemia cells was studied by 17O nuclear magnetic resonance during differentiation induced by dimethyl sulfoxide (Me2SO). While in noninduced cells water permeability was essentially constant during the growth period, in the Me2SO-induced cells there were two distinct periods at which the water permeability was increased by at least an order of magnitude. These periods correspond to approximately one doubling time and 6 days of growth. This change in water permeability is not due to direct interaction of Me2SO with the membrane but must be ascribed to structural changes in the membrane during the course of differentiation.