首页    期刊浏览 2024年12月11日 星期三
登录注册

文章基本信息

  • 标题:Translational specificity of Bacillus stearothermophilus ribosomes
  • 本地全文:下载
  • 作者:C S Chen ; T Nakamoto
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1978
  • 卷号:75
  • 期号:1
  • 页码:167-171
  • DOI:10.1073/pnas.75.1.167
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The translational specificity of Bacillus stearothermophilus ribosomes was studied by determining the effectiveness of various synthetic RNAs as templates at 37 degrees and at higher temperatures. The effectiveness of poly(G,U) was maximal at a G:U ratio of 1:3; it declined with lower G content because of reduced ribosomal affinity for the RNA and, with higher G, because of interference by secondary structure. The effectiveness of poly(A,C,G,U) also declined when secondary structure was increased by increasing (G+C) content. Escherichia coli ribosomes exhibited a similar specificity for poly-(G,U), but had a lower sensitivity to interference by RNA secondary structure. In both bacterial species, sensitivity to secondary structure was determined by the 30S ribosomal subunit.
国家哲学社会科学文献中心版权所有