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  • 标题:Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells
  • 本地全文:下载
  • 作者:H Koprowski ; W Gerhard ; C M Croce
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1977
  • 卷号:74
  • 期号:7
  • 页码:2985-2988
  • DOI:10.1073/pnas.74.7.2985
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:We have produced somatic cell hybrids between mouse myeloma cells and spleen cells derived from a BALB/c mouse immunized with purified influenza virus. The hybrid cells were found to produce large amounts of antibodies specific for the hemagglutinin of the virus and were able to induce tumor formation when injected into BALB/c mice.
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