期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1977
卷号:74
期号:10
页码:4595-4599
DOI:10.1073/pnas.74.10.4595
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Anti-Ig induced redistribution of different Ig subclasses was studied as a function of temperature and correlated with membrane phase transitions as revealed by electron spin resonance spectroscopy. Fluorescein isothiocyanate-coupled anti-IgG2 and anti-IgM antibodies induced patching and capping that proceeded with increasing rates from 2{degrees} to 40{degrees} (measured at 2{degrees} intervals). Characteristic temperatures marked the onset of discontinuities in such rate changes. IgG2-bearing lymphocytes displayed discontinuities at 14{degrees
关键词:membrane fluidity ; electron spin resonance spectroscopy