文章基本信息

标题：Similarities among hypervariable segments of immunoglobulin chains
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作者：T T Wu ; E A Kabat ; H Bilofsky 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1975
卷号：72
期号：12
页码：5107-5110
DOI：10.1073/pnas.72.12.5107
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：A human lambdaV (Mcg) and a human lambdaII (Vil) myeloma protein have identical sequences in their first hypervariable segments although they differ at 21 positions throughout the variable region. If a different structural gene is responsible for each subgroup, the findings favor insertion of information for the hypervariable or complementarity-determining segments.