文章基本信息

标题：X-ray fiber diffraction evidence for neighbor exclusion binding of a platinum metallointercalation reagent to DNA
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作者：P J Bond ; R Langridge ; K W Jennette 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1975
卷号：72
期号：12
页码：4825-4829
DOI：10.1073/pnas.72.12.4825
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Good quality x-ray diffraction patterns have been obtained of polycrystalline fibers containing 2-hydroxyethanethiolato(2,2'2"-terpyridine)platinum(II) bound to calf thymus DNA by intercalation. The photographs strongly support the neighbor exclusion binding model in which electron-dense platinum atoms are regularly distributed at 10.2 A intervals, every other interbase pair site.