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  • 标题:Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles
  • 本地全文:下载
  • 作者:J Summers ; A O'Connell ; I Millman
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1975
  • 卷号:72
  • 期号:11
  • 页码:4597-4601
  • DOI:10.1073/pnas.72.11.4597
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:DNA extracted from Dane particles has been characterized by gel electrophoresis and restriction enzyme cleavage with endonuclease R-HaeIII (from Hemophilus aegyptius). Dane particle DNA is proposed to be a double-stranded circular DNA approximately 3600 nucleotides in length containing a single-stranded gap of 600-2100 nucleotides. The endogenous DNA polymerase (DNA nucleotidyl-transferase; deoxynucleosidetriphosphate:DNA deoxynucleotidyltransferase; EC 2.7.7.7 ) reaction appears to repair this single-stranded gap.
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