文章基本信息

标题：Genome-wide location analysis reveals a role for Sub1 in RNA polymerase III transcription
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作者：Arounie Tavenet ; Audrey Suleau ; Géraldine Dubreuil 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2009
卷号：106
期号：34
页码：14265-14270
DOI：10.1073/pnas.0900162106
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Human PC4 and the yeast ortholog Sub1 have multiple functions in RNA polymerase II transcription. Genome-wide mapping revealed that Sub1 is present on Pol III-transcribed genes. Sub1 was found to interact with components of the Pol III transcription system and to stimulate the initiation and reinitiation steps in a system reconstituted with all recombinant factors. Sub1 was required for optimal Pol III gene transcription in exponentially growing cells.
关键词：Chip chip ; PC4 ; reinitiation ; TFIIIB