文章基本信息

标题：Oligomeric catechins: An enabling synthetic strategy by orthogonal activation and C(8) protection
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作者：Ken Ohmori ; Naoko Ushimaru ; Keisuke Suzuki 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2004
卷号：101
期号：33
页码：12002-12007
DOI：10.1073/pnas.0401651101
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Controlled formation of oligomeric catechins has become possible by an orthogonal synthetic strategy. Bromo-capping of the C(8) position of the flavan skeleton enabled the equimolar coupling of electrophilic and nucleophilic catechin derivatives, enabling an efficient synthetic strategy to complex catechin oligomers.