文章基本信息

标题：The essence of total synthesis
本地全文：下载
作者：K. C. Nicolaou ; Scott A. Snyder
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2004
卷号：101
期号：33
页码：11929-11936
DOI：10.1073/pnas.0403799101
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：For the past century, the total synthesis of natural products has served as the flagship of chemical synthesis and the principal driving force for discovering new chemical reactivity, evaluating physical organic theories, testing the power of existing synthetic methods, and enabling biology and medicine. This perspective article seeks to examine this time-honored and highly demanding art, distilling its essence in an effort to ascertain its power and future potential.