文章基本信息

标题：Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and -independent pathways
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作者：Hubertus Hochrein ; Beatrix Schlatter ; Meredith O'Keeffe 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2004
卷号：101
期号：31
页码：11416-11421
DOI：10.1073/pnas.0403555101
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Type I IFN production in response to the DNA virus herpes simplex virus type-1 (HSV-1) is essential in controlling viral replication. We investigated whether plasmacytoid dendritic cells (pDC) were the major tissue source of IFN-{alpha