文章基本信息

标题：Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-β during adipogenesis
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作者：Qi-Qun Tang ; M. Daniel Lane
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2000
卷号：97
期号：23
页码：12446-12450
DOI：10.1073/pnas.220425597
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Hormone induction of growth-arrested preadipocytes triggers mitotic clonal expansion followed by expression of CCAAT/enhancer-binding protein (C/EBP) and differentiation into adipocytes. The order of these events is critical because C/EBP is antimitotic and its expression prematurely would block the mitotic clonal expansion required for differentiation. C/EBP{beta
关键词：3T3-L1 preadipocyte ; adipocyte ; differentiation ; centromere ; mitotic clonal expansion