文章基本信息

标题：Base pair analogs in the gas phase
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作者：Joseph R. Roscioli ; David W. Pratt
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2003
卷号：100
期号：24
页码：13752-13754
DOI：10.1073/pnas.2333806100
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：A rotationally resolved electronic spectrum of the gas-phase dimer 2-aminopyridine{middle dot}2-pyridone, an analog of the adenine{middle dot}thymine base pair, has been observed and assigned, leading to precise measurements of its moments of inertia and preliminary determinations of its structure. A Watson-Crick configuration results, with N{middle dot}{middle dot}{middle dot}H--N and N--H{middle dot}{middle dot}{middle dot}O hydrogen bond lengths of 2.898 and 2.810 A, respectively. The two bases are found not to be coplanar; a dihedral angle of 6.1{degrees} between the base planes is also estimated from the measured moments of inertia. Possible chemical and biological implications of these results are discussed.