期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:2017
卷号:114
期号:15
页码:3873-3878
DOI:10.1073/pnas.1702654114
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:A change-point detection is proposed by using a Bayesian-type statistic based on the shortest Hamiltonian path, and the change-point is estimated by using ratio cut. A permutation procedure is applied to approximate the significance of Bayesian-type statistics. The change-point test is proven to be consistent, and an error probability in change-point estimation is provided. The test is very powerful against alternatives with a shift in variance and is accurate in change-point estimation, as shown in simulation studies. Its applicability in tracking cell division is illustrated.
关键词:Bayesian-type statistic ; shortest Hamilton path ; ratio cut ; minimum spanning tree ; cell division