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  • 标题:Guidance on allergenicity assessment of genetically modified plants
  • 作者:Hanspeter Naegeli ; Andrew Nicholas Birch ; Josep Casacuberta
  • 期刊名称:EFSA Journal
  • 印刷版ISSN:1831-4732
  • 出版年度:2017
  • 卷号:15
  • 期号:6
  • 页码:n/a-n/a
  • DOI:10.2903/j.efsa.2017.4862
  • 语种:English
  • 出版社:European Food Safety Authority (EFSA), Parma
  • 摘要:Abstract This document provides supplementary guidance on specific topics for the allergenicity risk assessment of genetically modified plants. In particular, it supplements general recommendations outlined in previous EFSA GMO Panel guidelines and Implementing Regulation ( EU ) No 503/2013. The topics addressed are non‐IgE‐mediated adverse immune reactions to foods, in vitro protein digestibility tests and endogenous allergenicity. New scientific and regulatory developments regarding these three topics are described in this document. Considerations on the practical implementation of those developments in the risk assessment of genetically modified plants are discussed and recommended, where appropriate.
  • 关键词:guidance;allergenicity assessment;newly expressed proteins;endogenous allergenicity;GMO
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