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标题：CORONARY ARTERY BYPASS GRAFT SURGERY OUTCOMES FOLLOWING 6.5 YEARS: A NESTED CASE–CONTROL STUDY
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作者：JAHANGIRY LEILA ; NAJAFI MAHDI ; ABBASALIZAD FARHANGI MAHDIEH 等
期刊名称：INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE
印刷版ISSN：2008-7802
出版年度：2017
卷号：8
期号：-
页码：0-0
语种：English
出版社：ISFAHAN UNIVERSITY OF MEDICAL SCIENCES
摘要：Background: Coronary artery disease (CAD) is the leading causes of mortality and morbidityin worldwide. This nested case–control study investigated the predictors of death in long?termfollow?up after coronary artery bypass graft surgery (CABG).
Methods: Cases were defined asCABG patients who died in the period of May 2006–March 2013. Controls were CABG patientswho were alive in the same period. Cases and controls were derived from an existing cohort, TehranHeart Center?Coronary Outcome Measurement. One hundred and fifty?nine patients in control groupwere randomly selected from 566 available patients in follow?up database. A series of simple andmultiple logistic regressions was performed in the context of univariate and multivariate analyses, respectively, for computing unadjusted and adjusted odds ratios and their confidence intervals (CI).
In the univariate analyses, demographic or cardiometabolic factors were entered separately, and formultivariate analysis, we got both significant risk factors from univariate analysis and the major riskfactors.
Results: The results of multivariate analyses showed that for age, the likelihood of mortalityincreases in CABG patients (95%CI: 1.1; 1.03–1.2; P (95%CI: 2.49; 0.9–6.3; P=0.039), smoking (95%CI: 4.38; 1.45–13.7; P=0.011), length of stay inhospital after CABG surgery (95%CI: 1.14; 1.0–1.24; P=0.001), total cholesterol (95%CI: 1.12; 1–1.2; P=0.001), and C?reactive protein (CRP) (95%CI: 1.12; 0.99–1.27; P=0.049) (all P Conclusions: The study results indicated that age, diabetes, cigarette smoking, PVD, long lengthof stay in hospital, elevated triglycerides, total cholesterol, CRP, and high?density lipoproteincholesterol were significant contributing to increased mortality after CABG. It seems that vulnerableolder patients continue to be at high risk with poor outcomes.
关键词：CARDIOMETABOLIC RISK FACTORS; CORONARY ARTERY BYPASS GRAFT SURGERY; MORTALITY; OUTCOME