文章基本信息

标题：Lexis Expansion: a prerequisite for analyzing time changing variables in a cohort study
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作者：Nitika Nitika ; Sidharth Sekhar Mishra ; Pallavi Lohani 等
期刊名称：Nepal Journal of Epidemiology
电子版ISSN：2091-0800
出版年度：2017
卷号：7
期号：2
页码：681-684
DOI：10.3126/nje.v7i2.17974
语种：English
出版社：International Nepal Epidemiological Association (INEA)
摘要：In a prospective analytical cohort study or a study involving a longer follow up, changing age of participants influence the relationship between exposure and outcome. Usually age at entry is incorporated in the regression model to adjust for age. However, this fails to fully explain and adjust for changing age. For this Lexis expansion, a concept by Wilhelm Lexis, allows the analyst to expand the observations as per age bands and check for confounding and interaction by changing age. Lexis expansion assumes the rates to be constant within an age band.
其他摘要：In a prospective analytical cohort study or a study involving a longer follow up, changing age of participants influence the relationship between exposure and outcome. Usually age at entry is incorporated in the regression model to adjust for age. However, this fails to fully explain and adjust for changing age. For this Lexis expansion, a concept by Wilhelm Lexis, allows the analyst to expand the observations as per age bands and check for confounding and interaction by changing age. Lexis expansion assumes the rates to be constant within an age band.
关键词：Lexis Expansion;variable;cohort study