文章基本信息

标题：Clinical neurorestorative progresses in cerebral palsy
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作者：Alok Sharma ; Tongchao Geng ; Hemangi Sane 等
期刊名称：Journal of Neurorestoratology
电子版ISSN：2324-2426
出版年度：2017
卷号：5
页码：51-57
DOI：10.2147/JN.S99014
语种：English
出版社：Dove Medical Press Ltd
摘要：Cerebral palsy (CP), group of permanent nonprogressive clinical disorders in children, is caused by damage to the immature brain. Conventionally available treatments for CP are mainly targeted toward management of its symptoms. With the upcoming field of neurorestorative strategies, we are now able to repair the core brain damage in CP. There are various drugs, stem cells, etc, which have been implicated to have neurorestorative properties. Autologous bone marrow stem cells, umbilical cord stem cells, neural stem cells, and olfactory ensheathing cells have shown the safety and efficacy in preliminary studies. Here, we review the different medicines and cell types that have shown beneficial effects in clinical studies. We propose that combination strategies may be the future of neurorestoration.
关键词：stem cell therapy; bone marrow; umbilical cord; neural cells; regenerative medicine; brain