文章基本信息

标题：Novel Methods for Measuring Depth of Anesthesia by Quantifying Dominant Information Flow in Multichannel EEGs
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作者：Kab-Mun Cha ; Byung-Moon Choi ; Gyu-Jeong Noh 等
期刊名称：Computational Intelligence and Neuroscience
印刷版ISSN：1687-5265
电子版ISSN：1687-5273
出版年度：2017
卷号：2017
DOI：10.1155/2017/3521261
出版社：Hindawi Publishing Corporation
摘要：In this paper, we propose novel methods for measuring depth of anesthesia (DOA) by quantifying dominant information flow in multichannel EEGs. Conventional methods mainly use few EEG channels independently and most of multichannel EEG based studies are limited to specific regions of the brain. Therefore the function of the cerebral cortex over wide brain regions is hardly reflected in DOA measurement. Here, DOA is measured by the quantification of dominant information flow obtained from principle bipartition. Three bipartitioning methods are used to detect the dominant information flow in entire EEG channels and the dominant information flow is quantified by calculating information entropy. High correlation between the proposed measures and the plasma concentration of propofol is confirmed from the experimental results of clinical data in 39 subjects. To illustrate the performance of the proposed methods more easily we present the results for multichannel EEG on a two-dimensional (2D) brain map.