文章基本信息

标题：Metabolic and Anatomic Abnormalities Associated with Pediatric Nephrolithiasis: a Cross-Sectional Study
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作者：Mohsen Akhavan Sepahi ; Seyed Shahin Eftekhari ; Sara Shahmoradi 等
期刊名称：International Journal of Pediatrics
印刷版ISSN：2345-5047
电子版ISSN：2345-5055
出版年度：2017
卷号：5
期号：5
页码：4833-4838
DOI：10.22038/ijp.2017.22705.1896
语种：English
出版社：Mashhad University of Medical Sciences
其他摘要：Background Pediatric nephrolithiasis is a condition the prevalence of which varies geographically with multiple etiologies. The aim of this study was to determine possible concomitant anatomic and metabolic disturbances in children with nephrolithiasis and to answer the questions regarding the role of each metabolic and anatomic abnormality. Materials and Methods Between 2007 and 2015, 1,080 patients referred to our pediatric hospital of Hazrat Masumeh in Qom city, with the diagnosis of nephrolithiasis. Complete history from each eligible patient has taken using a prespecified data extraction form. Then, each child was referred for metabolic and anatomical evaluation using laboratory and imaging tests. Results According to the extracted data, 92% of our patients had at least one concomitant metabolic disorder and 12.5% had an anatomic abnormality. Recorded metabolic disorders in our series were hypocitraturia (56.9%), hyperuricosuria (21.4%), hypercalciuria (19.3%), hyperoxaluria (14.7%), phosphaturia (11.4%), and cystinuria (1.4%). According to data analysis, 12.5% of patients had an anatomical abnormality of which the ureteropelvic junction obstruction and vesicoureteral reflux were the most common. Conclusion The current study showed that the most common abnormalities in association with nephrolithiasis were metabolic disturbances, which highlight the importance of further metabolic study, even in patients with anatomical abnormalities.
其他关键词：Anatomic abnormalities; Children; Metabolic abnormalities; Pediatric nephrolithiasis