文章基本信息

标题：Role of Clinical Human Exposure Study in Health Risk Assessment for Air Pollutants
本地全文：下载
作者：Jun KAGAWA
期刊名称：生活衛生
印刷版ISSN：0582-4176
电子版ISSN：1883-6631
出版年度：1997
卷号：41
期号：2
页码：45-54
DOI：10.11468/seikatsueisei1957.41.45
出版社：Osaka Urban Living and Health Association
摘要：The health risk assessment for evaluating a causal relationship between the observed symptoms and air pollutants was made by using the results of the epidemiological, clinical human exposure and animal exposure studies. In Japan, the first photochemical air pollution episode was reported in 1970. These episodes were observed often in middle and high school students in Tokyo and Osaka who exercised in the daytime during the photochemical air pollution season. The observed symptoms were divided into three categories: irritating symptoms of eye, throat and airway; general symptoms such as headache, nausea, dizziness and lassitude, etc., and neurological symptoms such as numbness in the extremities, convulsions, and unconsciousness. The results of clinical humann exposure studies showed that the irritating symptoms of airway were due mainly to exposure to ozone. Although the mechanisms of the general and neurological symptoms other than respiratory irritation could not be determined in these studies, a level of 0.15ppm ozone produced significant respiratory effects when the subject undertook light exercise. A role of clinical human exposure study was also discussed in evaluating a short-term guideline value for each air pollutant.
关键词：Photochemical air pollution;Health risk assessment;Clinical human exposure study;Air pollutants