文章基本信息

标题：防虫・防ダニ家庭用品中のピレスロイド系農薬 : 共力剤及び忌避剤の分析と変異原性
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作者：宇都宮暁子 ; 長谷川一夫 ; 森康明等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1997
卷号：43
期号：6
页码：366-375
DOI：10.1248/jhs1956.43.366
出版社：The Pharmaceutical Society of Japan
摘要：The analytical method using GC-MS was developed to determine simultaneously eleven chemicals, such as pyrethroid pesticides (empenthrin, allethrin, tetramethrin, resmethrin, phenothrin and permethrin), synergists (1, 1-oxybis (2, 3, 3, 3-tetrachloropropane) (S-421), diethyl phtalate and piperonyl butoxide), a repellent (N, N-diethyl-m-toluamide (DEET)) and dibutyl phthalate, in moth/mite-proofed household products. The eleven chemicals were extracted from the moth-proofing agents and covers for fabric, the moth/mite-proofing sheets and other related products by ultrasonification in acetone for 30 min. The recoveries of the 10 chemicals, except dibutyl phthalate, were found in the mite-proofed paper bag for a vacuum cleaner were 100-103% on the average. The concentration of pyrethroid pesticides which were detected in 42 brands of various household products ranged 0.46-357 mg/g for empenthrin, 0.39-11.8 mg/g for allethrin, 0.24-2.94 mg/g for tetramethrin, 0.11-110 mg/g for permethrin, and 4.47 mg/g for phenothrin, respectively. S-421 and piperonyl butoxide, synergists, ranged 0.06-37.9 mg/g, and 0.06-6.99 mg/g, respectively. The mutagenic responses of the acetone solutions extracted from the household products and S-421 standards ranged from 2.1 to 6.6 revertants (rev.)/mg and 215 rev./mg, respectively. The contribution of S-421 to the mutagenicity of the product extracts was estimated to be from 17.8 to 74.7%.
关键词：pyrethroid pesticide;GC-MS analysis;mutagenicity;synergist;repellent;1, 1-oxybis (2, 3, 3, 3-tetrachloropropane) (S-421);household product