文章基本信息

标题：白ネズミにおける脾臓肥大とF-cells値との関係
本地全文：下载
作者：久岡文子 ; 佐川寿栄子 ; 三木武久等
期刊名称：日本栄養・食糧学会誌
印刷版ISSN：0287-3516
电子版ISSN：1883-2849
出版年度：1978
卷号：31
期号：1
页码：59-65
DOI：10.4327/jsnfs1949.31.59
出版社：Japanese Society of Nutrition and Food Science
摘要：Blood volume, F-cells value and blood cell pools in liver and spleen were measured in splenectomized and splenomegaly rats. Splenomegaly of the rats was induced by injecting methyl cellulose and the weight of the spleen increased by 5 folds of the normal rat. The splenic pool of blood cells measured by a tracer method revealed 1.1% of the total red cell volume in normal rats, whereas that of splenomegaly rats was increased to 13.3% of the total red cell volume. In the rats with the enlarged spleen, the concentration of circulating hemoglobin and the hematocrit value were significantly reduced, but the total volume of red cell mass was not reduced in comparison with normal control rats, because the expanded splenic pool of red cells was accounted for the total red cell volume. An expansion of the plasma volume was observed in the rats with the enlarged spleen, and the expansion of the plasma volume resulted in an increase in blood volume and a lowering of the concentration of hemoglobin and the hematocrit value of circulating blood (hemodilution). A concomitant decrease in the body hematocrit and cardiac hematocrit was observed in thesplenomegaly rats, therefore the ratio of body hematocrit to cardiac hematocrit was identical to thatof normal and splenectomized rats. Red cell volume was reduced significantly when an enlarged spleen of the rat was removed just prior to the measurement, and decreased volume was matched to the red cell pool in the enlarged spleen. Accordingly, the ratio of body hematocrit to the cardiac hematocrit was decreased significantly, mainly due to the decreased body hematocrit or decreased red cell mass.