文章基本信息

标题：裁判化学における薬毒物の系統的分析法に関する研究(第2報)Retention Indexによる同定のためのキャピラリーカラムガスクロマトグラフィーの利用
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作者：大山信行 ; 佐野敏幸 ; 庄山正敏等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1987
卷号：33
期号：5
页码：342-348
DOI：10.1248/jhs1956.33.342
出版社：The Pharmaceutical Society of Japan
摘要：The simultaneous determination of 110 compounds including pesticides, hypnotics, local anesthetics, psychotropics, narcotics, etc., was examined by means of retention index on gas chromatography (GC). Temperature programmed GC using fused- silica capillary column CBP-1 (0.53 mm i. d.×12 m) was very effective in this study as compared with CBP-10 (0.33 mm i. d.×25 m) and some packed columns. All of the compounds except benzoximate, cloxazolam and oxazepam could be detected as good symmetrical peaks less than 100 minutes under the conditions of 120-250°C/(6°C/min) as oven temperature, 270°C as injection temperature, 0.2 kg/cm² as carrier gas (N₂) pressure (velocity, 90.9 cm/s) on CBP-1. A search window of these retention indices could be estimated about 20, then the discriminating powers of a combination of this data and TLC screening system mentioned earlier (Ref. 1), were 0.995, 1.00, 1.00, 0.996 and 1.00 in I, II, II', III and IV division, respectively.
关键词：retention index;GC;fused-silica capillary column;forensic chemistry;poisonous compound;simultaneous determination