文章基本信息

标题：四塩化炭素投与ラットの体内におけるヒアルロン酸, コンドロイチン硫酸及びデルマタン硫酸の変動
本地全文：下载
作者：元木一宏 ; 谷川雅彦 ; 穐山浩等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1992
卷号：38
期号：1
页码：63-68
DOI：10.1248/jhs1956.38.63
出版社：The Pharmaceutical Society of Japan
摘要：The effect of subcutaneous administration of carbon tetrachloride to rats on the quantitative and qualitative changes of glycosaminoglycans, i.e., hyaluronic acid (HA), chondroitin sulfates (CS) and dermatan sulfate (DS), in the liver, kidney, spleen, plasma and urine was investigated. In the cases of the liver, kidney and plasma, no difference was found in the amount of glycosaminoglycans between carbon tetrachloride-treated rats and normal ones. On the other hand, all of the glycosaminoglycans examined in this study (HA, CS and DS) increased considerably in the spleen and urine after the repeated carbon tetrachloride administrations.
关键词：glycosaminoglycan;hyaluronic acid;chondroitin sulfate;dermatan sulfate;carbon tetrachloride;liver;spleen;kidney;plasma;urine