文章基本信息

标题：多変量解析法を用いた赤外分光分析による混合した有機化合物の定量
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作者：奥山修司 ; 三井利幸 ; 藤村義和等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1993
卷号：39
期号：3
页码：213-218
DOI：10.1248/jhs1956.39.3_213
出版社：The Pharmaceutical Society of Japan
摘要：Multivariate analysis was applied to the determination of a mixed organic compound by Fourier transform infrared spectroscopy (FT-IR) and each component was measured accurately without pretreatment such as separation procedure or addition of internal standard substance. For example, the mixture of tetracaine hydrochloride and glucose or methamphetamine hydrochloride and ephedrine hydrochloride (known blend composition) was measured by FT-IR. The obtained spectra were expressed by relative values to provide a data base. A mixture with unknown blend composition ratio (unknown sample) was dealt with in a similar manner. The obtained data were used for the multivariate analysis such as quantification IV, cluster analysis, cluster analysis from deviation and principal component analysis. The rough blend composition ratio of unknown sample was estimated and the data base for calibration curve was selected. Furthermore, the blend composition ratio was determined more accurately by the principal component scores.
关键词：multivariate analysis;FT-IR;glucose;tetracaine hydrochloride;methamphetamine hydrochloride;ephedrine hydrochloride