文章基本信息

标题：The Effect of Several Antipyretic Analgesics on Mitomycin C-Induced Mutagenesis Using the Wing Spot Test in Drosophila melanogaster
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作者：TAKAHIKO SATO ; KOUITI NAGAOKA ; HISAMITSU NAGASE 等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1996
卷号：42
期号：2
页码：136-141
DOI：10.1248/jhs1956.42.136
出版社：The Pharmaceutical Society of Japan
摘要：The effect of several antipyretic analgesics on mitomycin C-induced mutagenesis was investigated using the wing spot test in Drosophila melanogaster. Aspirin, ibuprofen and indomethacin showed strong antimutagenicity, while the antimutagenicity of acetaminophen and ethenzamide were weaker. Aspirin inhibited chromosome recombination. A considerable part of the antimutagenicity of aspirin, ibuprofen and indomethacin can be explained by bioantimutagenicity.
关键词：antimutagenicity;bio-antimutagenicity;chromosome recombination;antipyretic analgesic;wing spot test;Drosophila melanogaster