文章基本信息

标题：ビフェニル投与により雄ラットの膀胱内に認められた結石の成分分析
本地全文：下载
作者：大西誠 ; 武信 ; 佐川みつ代等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1998
卷号：44
期号：4
页码：256-263
DOI：10.1248/jhs1956.44.256
出版社：The Pharmaceutical Society of Japan
摘要：The components of biphenyl induced urinary bladder calculus in the male rats were studied using HPLC coupled with mass spectrometry/mass spectrometry (LC-MS/MS), IR and inductive coupled plasma (ICP). Two peaks in the calculus components were detected by HPLC and LC-MS/MS. The peaks were identified as 4-hydroxybiphenyl sulfate (4-HBPSC) and 4, 4'-dihydroxybiphenyl sulfate (4, 4'-DHBPSC). 4-HBPSC was accounted for 54.6% and 4, 4'-DHBPSC was accounted for 1.5% by LC-MS/MS. 4-HBPSC was main component by these results and IR. Inorganic elements of urinary bladder calculus were accounted for 25% by ICP.
关键词：LC-MS/MS;biphenyl;calculus;sulfate;urinary bladder;rat