文章基本信息

标题：希土類元素の生体影響に関する研究(第一報)ジスプロシウム, ユーロピウム, イッテルビウム及びイットリウムの生体試料からの分析法の検討
本地全文：下载
作者：中村優美子 ; 長谷川ゆかり ; 外海泰秀等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1991
卷号：37
期号：1
页码：28-38
DOI：10.1248/jhs1956.37.28
出版社：The Pharmaceutical Society of Japan
摘要：The analytical method of 4 kinds of rare earth elements i.e. dysprosium (Dy), europium (Eu), ytterbium (Yb) and yttrium (Y) from the biological materials were investigated. 1) Three kinds of methods, i.e. atomic absorption spectrometry (AAS), flame emission spectrometry (FES) and inductively coupled plasma atomic emission spectrometry (ICP-AES) were compared. Most sensitive and reliable method was ICP-AES, so the determination of 4 kinds of rare earth elements was performed by ICP-AES. 2) Two kinds of solvent extraction methods were investigated. None of APDC-MIBK (ammonium pyrrolidinedithiocarbamate/methyl isobuthyl ketone) system nor D2-EHPA (di (2-ethylhexyl) phosphoric acid) system revealed sufficient results. 3) Dry ashing procedure was investigated for the biological materials. Recoveries of Dy, Eu, Yb and Y (25-2500 ppm added) were 44.0-96.5% for the liver, whole blood, spleen and kidney for which the ashing was complete ; contrarily, those were 35.5-78.9% for the feces and femur for which the ashing was incomplete. 4) Wet digestion method was investigated for the biological materials. Recoveries of Dy, Eu, Yb and Y were 77.6-100.7% in case of H₂SO₄-HNO₃ digestion (250 ppm added) and 85.3-100.5% in case of HNO₃ digestion (25 ppm added). The HNO₃ digestion method was better than the H₂SO₄-HNO₃ digestion method because of no CaSO₄ precipitation in the former method. Therefore, it was suggested that the best analytical method for these 4 kinds of rare earth elements from the biological materials was the combination of wet digestion method by using HNO₃ with ICP-AES.
关键词：rare earth elements;dysprosium;europium;ytterbium;yttrium;ICP-AES;wet digestion method;atomic absorption spectrometry;dry ashing procedure