文章基本信息

标题：パラコート感応性膜電極の作製と裁判化学への応用
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作者：渡辺清之 ; 岡田邦夫 ; 勝孝等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1992
卷号：38
期号：2
页码：142-148
DOI：10.1248/jhs1956.38.142
出版社：The Pharmaceutical Society of Japan
摘要：A paraquat-sensitive electrode was constructed by use of a poly (vinyl chloride)-based membrane containing sodium tetrakis [3, 5-bis (trifluoromethyl) phenyl] borate as an ion exchanger and 2-fluoro-2'-nitrodiphenyl ether as a membrane solvent. The minimum detection limit of paraquat was 5×10^-7M. The calibration slope of the electrode in linear region was 28 mV/decade. The selectivity coefficients against Na⁺, K⁺, Mg²⁺ and Ca²⁺ were less than 10^-4, and substantially, these inorganic ions did not interfere with the response to paraquat. This electrode was utilized for a criminal investigation. Paraquat added intentionally to drinks such as juice, cola and milk in cases of murder can speedily be measured by the paraquat-sensitive electrode without separating the herbicide from assay mixtures. By using the present electrode, we could estimate paraquat down to 5×10^-5M contained in juice. This sensitivity was sufficient enough for the detection of paraquat used in a crime : when the lethal dose of paraquat (2.4 g/a man of 60 kg) was mixed with juice (250 ml), the concentration became about 40 mM. The electrode was also applied to a clinical analysis, and paraquat in the serum could successfully be detected down to 2μM.
关键词：ion-selective electrode;potentiometry;paraquat;paraquat-sensitive electrode;membrane electrode;forensic chemistry;criminal investigation;electrochemical analysis;analytical method