文章基本信息

标题：可溶性アルギン酸ナトリウムのコレステロール, Trp-P-1及びアフラトキシンB1のラットでの排泄に及ぼす影響
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作者：渡辺一弘 ; 岩田一幸 ; 丹代優香等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1992
卷号：38
期号：3
页码：258-262
DOI：10.1248/jhs1956.38.258
出版社：The Pharmaceutical Society of Japan
摘要：The effects of soluble sodium alginate of average molecular weight (A.M.W.), 1×10⁴ (AG-1), 5×10⁴ (AG-5) or 1×10⁵ (AG-10) on the excretion of ³H-labeled cholesterol, Trp-P-1 and aflatoxin B₁ in rat were compared with those of commercially available sodium alginate (A.M.W. : 2.7×10⁶, AG-270) and polydextrose. In rats administered ³H-cholesterol, the simultaneous administration of AG-10 or AG-270 (100mg/kg) significantly increased the amount of isotope excreted in feces. The administration of AG-5 or AG-10 (1000 mg/kg) after the administration of the tested compounds increased the amounts isotope excretion into feces, and decreased significantly those into urine. The administration of AG-1, however, showed no effect. These results indicate that AG-5 and AG-10 exhibited the same accelerating effects on the excretion of the tested compounds as AG-270.
关键词：soluble sodium alginate;excretion;cholesterol;Trp-P-1;aflatoxin B1;rat;sodium alginate;alginate;alginic acid;dietary fiber