首页    期刊浏览 2024年12月05日 星期四
登录注册

文章基本信息

  • 标题:TLCによる中毒起因物質としての農薬の迅速スクリーニング法
  • 本地全文:下载
  • 作者:森 博美 ; 佐藤 孝彦 ; 永瀬 久光
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:1994
  • 卷号:40
  • 期号:1
  • 页码:101-110
  • DOI:10.1248/jhs1956.40.101
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:When the patients who were suspected to take pesticides were carried into hospital, rapid identification of pesticides was mostly necessary. We investigated the rapid and simple screening method for the identification of pesticides in the case of toxicosis in general hospital using thin layer chromatography (TLC). We selected 46 common pesticides having many toxications. They were analyzed by fluorescent silica gel TLC with four developing solvent systems and three detection methods. As the results, 24 pesticides were detected at less than 0.5 μg by observation under UV radiation. Twelve of 46 pesticides reacted with Dragendorff reagent. Especially paraquat and diquat were highly sensitive to it. 4-(p-nitrobenzyl) pyridine-tetraethylenepentamin reagent reacted to all organophosphorous compounds and their lower detection limits were 0.03-20 μg over a wide range. Standard deviations of Rf values were very small. The good recoveries of pesticides were obtained from spiked serum samples. This method enabled us to identify pesticides as the cause substances of toxicosis rapidly from the serum and returned gastoric lavege solution from patients.
  • 关键词:emergency pesticide screening;silica gel TLC;pesticide poisoning;clinical toxicology
国家哲学社会科学文献中心版权所有