文章基本信息

标题：生薬水抽出物の突然変異原性とQuercetinの寄与
本地全文：下载
作者：野坂富雄 ; 山田さゆり ; 広瀬義文等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1994
卷号：40
期号：1
页码：66-70
DOI：10.1248/jhs1956.40.66
出版社：The Pharmaceutical Society of Japan
摘要：Water extracts of 41 commercial crude drugs were subjected to screening studies for mutagenicity by means of the reversion assay with Ames'strain TA 98 and TA 100 of Salmonella typhimurium. Ten of the water extracts were found to be positive in the Ames test. In general, these observed mutagenicity was, however, quite weak. Among them we attempted to isolate a major mutagenic component from Sophorae flos which was markedly active, and was regarded as quercetin.
关键词：crude drug;mutagenicity;water extract;Ames test;Sophorae flos;quercetin