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  • 标题:総合感冒剤中のヘスペリジンの比色定量法
  • 本地全文:下载
  • 作者:松沢 孝信 ; 高島 正市 ; 上田 雅子
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:1977
  • 卷号:23
  • 期号:4
  • 页码:223-228
  • DOI:10.1248/jhs1956.23.223
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Colorimetric determination of hesperidin in cold cure preparations was examined. Hesperidin reacted with diethyl-p-phenylenediamine in slight alkalinity, with the use of potassium ferricyanide as the oxidation agent. The reaction product was extracted with isobutanol and this extract solution, colored blue, had an absorption maximum at 650 nm. This followed the Lambert-Beer's law in the concentration range of 30-210 μg/3 ml of hesperidin. Several chemicals contained in the preparations interfered in this measurement but they were removed by extraction with acetone or water.
  • 关键词:hesperidin;flavonoids;colorimetry;indophenol reaction method;anti-cold pharmaceutical preparations
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