文章基本信息

标题：Effect of Intraperitoneal Injection of Vibrio parahaemolyticus on the Carbohydrate Metabolism in Mice
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作者：OSAMU SAKAGUCHI ; SHUHEI SAKAGUCHI ; NOBUKO TSUNODA 等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1977
卷号：23
期号：6
页码：339-344
DOI：10.1248/jhs1956.23.339
出版社：The Pharmaceutical Society of Japan
摘要：The effects of intraperitoneal administration of Vibrio parahaemolyticus pathogenic strain on carbohydrate metabolism in mice at varying administration doses were examined. The content of liver glycogen in mice at 5 hr after injection decreased in inverse proportion to the increase of the dose of viable pathogen. On the other hand, the level of blood sugar in mice changed effectively with an increase in the dose, and at the dose of 0.8 mg (2.72×10⁵ cells) a distinct hypoglycemia appeared within 5 hr after injection. The activities of hepatic phosphorylase and G-6-Pase showed a tendency similar to the rise and the fall in the levels of blood sugar. The result of this experiment suggests a complexicity of metabolic response in host to the aggression of pathogen.
关键词：Vibrio parahaemolyticus;carbohydrate metabolism;hepatic glycogen content;blood sugar level;hepatic phosphorylase;G-6-Pase;hypoglycemia