文章基本信息

标题：硝酸塩および亜硝酸塩の生体内運命
本地全文：下载
作者：石綿肇 ; 谷村顕雄
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1982
卷号：28
期号：4
页码：171-183
DOI：10.1248/jhs1956.28.4_171
出版社：The Pharmaceutical Society of Japan
摘要：Ingestion, absorption, metabolism and excretion of nitrate and nitrite in humans and experimental animals are described on the viewpoint that carcinogenic N-nitroso compounds are formed by the reaction of nitrite with amines or ureides. Although nitrate is an inactive substance on animals and most of that administered is excreted in the urine, nitrite which is derived from nitrate in vivo by microorganisms in the digestive tracts has highly pharmacological and biochemical activities. The latest problems on the possibility of the nitrification in the body and the nitrate balance are also reviewed. It seems that nitrate highly affects the human health because the substance is easily reduced to nitrite in the body.
关键词：nitrate;nitrite;absorption;metabolism;excretion;ingestion;nitrate balance;human;experimental animal;N-nitroso compound