文章基本信息

标题：Reaction of 2, 4-Lutidine 1-Oxide and 2, 4-Dimethylquinoline 1-Oxide with Acetic Anhydride
本地全文：下载
作者：Sunao Furukawa
期刊名称：Chemical and Pharmaceutical Bulletin
印刷版ISSN：0009-2363
电子版ISSN：1347-5223
出版年度：1955
卷号：3
期号：6
页码：413-416
DOI：10.1248/cpb1953.3.413
出版社：The Pharmaceutical Society of Japan
摘要：2, 4-Lutidine 1-oxide was converted to 2-hydroxymethyl-4-methylpyridine and 2-methyl-4-hydroxymethylpyridine by reaction with acetic ahydride, and its formation ratio was about 5 : 1. Besides these, 3-hydroxy-2, 4-lutidine was obtained as a phenolic base. In the case of the reaction of 2, 4-dimethylquinoline 1-oxide with acetic anhydride, 2-hydroxymethyllepidine and a small amount of 3-hydroxy-2, 4-dimethylquinoline were obtained but not 4-hydroxymethylquinaldine.