文章基本信息

标题：大麻草の裁判化学的研究III. : 大麻成分検出法の実際鑑定への応用(2)
本地全文：下载
作者：荒牧繁一郎 ; 富安温子 ; 吉村英敏等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1968
卷号：14
期号：5
页码：266-270
DOI：10.1248/jhs1956.14.266
出版社：The Pharmaceutical Society of Japan
摘要：The previous study on marihuana smoking indicated that the addicts would inhale about half amount of three main constituents, cannabidiol (CBD), tetrahydrocannabinol (THC) and cannabinol (CBN) in marihuana cigarettes, and suggested that some of the constituents might be excreted as unchanged or conjugated forms into the urine of these addicts. The present study was undertaken to confirm this possibility using rabbits. It was found in this experiment that free marihuana constituents in urine was extracted effectively with CHCl₃ during 10 hr under the pH 3. It was also shown that treatment of the urine with either 5% HCl or β-glucuronidase was necessary for detection of marihuana constituents in the urine before the extraction. Applying these procedures, CBN was detected in the urine of rabbits injected either CBN or ganja extract which contained a considerable amount of CBN. However, the excretion of any constituent could not be confirmed in the urine of either CBD or THC treated rabbits.