文章基本信息

标题：医薬品の放射線殺菌 I : クロロフィル製剤の放射線殺菌その1
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作者：佐藤健二 ; 伊藤宣夫 ; 岡充等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1966
卷号：12
期号：4
页码：195-198
DOI：10.1248/jhs1956.12.195
出版社：The Pharmaceutical Society of Japan
摘要：The application of radiation to the sterilization of drugs was studied using water soluble chlorophyll derivatives. Copper chlorophyll, methionine cobalt chlorophyll, and 5, 6-dimethyl benzimidazole cobalt chlorophyll, in solid state were irradiated with ⁶⁰Co γ-rays. No detrimental effect on the chemical properties was observed at a dose of 3 Mrad. The sterility test was performed according to the direction in the Japanese Pharmacopoeia, Ed. VII. An adequate dose for the sterilization of chlorophyll derivatives is estimated to be 1∼2 Mrad.