文章基本信息

标题：水道水の衛生化学的研究次亜塩素酸の人血球の機能にあたえる影響について
本地全文：下载
作者：安藤正典 ; 佐谷戸安好 ; 外村正治等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1972
卷号：18
期号：1
页码：13-18
DOI：10.1248/jhs1956.18.13
出版社：The Pharmaceutical Society of Japan
摘要：As a model experiment for the study of the effect of free chlorine in supplying water on living organisms, effect of hypochlorite on the functions of human blood cells was examined. It was thereby revealed that human erythrocytes were readily hemolyzed by hypochlorite in a concentration as small as 1 ppm and that their agglutinability with certain phytohemagglutinins was clearly enhanced by their treatment with hypochlorite. Further, the blastogenesis of human peripheral lymphocytes in the culture with PHA-M was somewhat facilitated in the presence of hypochlorite in the cutture medium. These results can be explained by the assumption that hypochlorite modifies the surface structure of human blood cells so as to make the receptor sites on the cell surface more accessible to phytohemaglutinins.