文章基本信息

标题：β-ベンゾイルアクリル酸エチルとリボヌクレオチド類の反応について
本地全文：下载
作者：浮田忠之進 ; 早津彦哉
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1971
卷号：17
期号：2
页码：88-91
DOI：10.1248/jhs1956.17.88
出版社：The Pharmaceutical Society of Japan
摘要：Ethyl trans-β-benzoylacrylate (t-BAE), which is known to be a degradation product of ethyl α-(2-hydroxyethylamino)-β-benzoylpropionate, and antimicrobial agent against Hiochi bacteria, was checked for its reactivity toward nucleic acid components. t-BAE is capable of reacting with 5'-guanylic and 5'-uridylic acids, but not with 5'-adenylic or 5'-cytidylic acid. These reactions proceed faster in alkaline solutions than in neutral solutions. Alkylations at the N¹ position of guanine and the N³ position of uracil are probably the reactions that take place.