文章基本信息

标题：無機水銀の消化管吸収(第1報)酸化第二水銀のラットにおける吸収および体内分布
本地全文：下载
作者：木村良平 ; 貞千恵子 ; 遠藤哲也等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1980
卷号：26
期号：4
页码：199-203
DOI：10.1248/jhs1956.26.199
出版社：The Pharmaceutical Society of Japan
摘要：Most of mercuric oxide (HgO) administered p.o. to rats (5 mgHg/kg) was excreted in feces, and about 2 % of the dose was excreted in urine. The distribution of mercury in rat tissues after the oral administration of HgO was similar to that after the oral administration of the same molar dose of mercuric chloride. Mercury concentrations in the blood after the administration of HgO into the stomach or small intestine of the pyrolus-ligated rats were similar to those after the administration of the same molar dose of mercuric chloride. Taking into account the low degree of dissociation, these results suggested that HgO was able to be absorbed from the gastro-intestinal tract without transformation to mercuric chloride.
关键词：mercuric oxide;mercuric chloride;gastro-intestinal absorption;distribution in tissues;excretion