文章基本信息

标题：Studies on the Toxicity of Silver Ion in Water Filtered through a Household Water Purifier Equipped with a Silver-Coated Charcoal Filter
本地全文：下载
作者：KATSUHIKO NAKAMURO ; YASUYOSHI SAYATO
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1986
卷号：32
期号：1
页码：28-33
DOI：10.1248/jhs1956.32.28
出版社：The Pharmaceutical Society of Japan
摘要：The elution patterns of silver ion from a household water purifier equipped with a silver-coated charcoal filter were investigated under domestic-type conditions and chromosomal aberration tests on human leukocyte cultures and cultured mammalian fibroblast cells were carried out in order to clarify the genetic toxicity of silver ion. New household water purifiers were used for the following elution studies. Two short-term elution tests showed that the concentration of silver ion in the eluate from a household water purifier was about 30 μg/l immediately after opening the tap, and fell to about 15 μg/l when 8 l of water had continuously passed through the purifier. The levels of silver ion in a long-term elution test for three months ranged from 13.0 to 28.5 μg/l. No silver ion was detected in tap water which had not been passed through the household water purifier (less than 1 μg/l). No significant chromosomal aberrations were induced by silver ion in human leukocyte cultures. However, the cytogenetic assay by using mammalian fibroblast cells suggested that silver ion might possess weak clastogenicity.
关键词：chromosomal aberration;household water purifier;human leukocyte;mammalian fibroblast cell;silver-coated charcoal filter;silver ion;tap water;clastogenicity