文章基本信息

标题：Forms of Chromium in Rat Blood Treated in Vivo and in Vitro with Na2 51CrO4 and 51CrCl3
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作者：KATSUHIKO NAKAMURO ; YASUYOSHI SAYATO
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：1986
卷号：32
期号：2
页码：123-127
DOI：10.1248/jhs1956.32.123
出版社：The Pharmaceutical Society of Japan
摘要：The forms of chromium and the interaction of radiolabelled chromium chloride and sodium chromate with the constituents of red blood cells and plasma in vivo and in vitro were investigated by Sephadex gel chromatographic techniques. The major chemical form in plasma treated with trivalent chromium was chromium-binding protein, and that in plasma treated with hexavalent chromium was a low molecular chromum complex possessing high ability to permeate through the red cell membrane. The form of chromium in stroma-free hemolysate after hexavalent chromium treatment was considered to be a chromium complex which bound easily to hemoglobin. After trivalent chromium treatment, a chromium complex binding easily to higher molecular proteins than hemoglobin was found in stroma-free hemolysate.
关键词：existing chemical form;hexavalent chromium;trivalent chromium;rat blood;plasma;stroma-free hemolysate;red cell permeability;gel filtration