摘要:We investigated the generation of mutagenicity by heating in fish meats with various water contents and in model system solutions containing creatinine, glucose and glycine. Comparison of the formation of mutagenicity in fish meats heated under air and steam suggested that loss of water accelerated the generation of mutagenicity. Experiments with the model system solutions indicated that the mutagenic activity produced in water alone was much less than that produced in the 10% water-diethylene glycol (or dioxane) system. Thus, a large amount of water inhibited the formation of the mutagenicity, and loss of water stimulated it. It seems unlikely that the activity of water influenced the formation of mutagenicity.