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标题：EXCITATION BY LYONIOL-A OF VAGAL AFFERENT NERVES AND THE REFLEX AUTONOMIC AND SOMATIC ACTIONS IN RATS
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作者：HIDEKI ONO ; HIDEOMI FUKUDA ; YOSHIHISA KUDO 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1981
卷号：4
期号：12
页码：940-946
DOI：10.1248/bpb1978.4.940
出版社：The Pharmaceutical Society of Japan
摘要：Lyoniol-A (2 mg/kg, i.v.), a toxic component isolated from the Ericaceous tree, markedly caused the increase in rate of discharges from vagal afferent nerves in the rat. This agent also caused respiratory depression, hypotension and the relief of decerebrate rigidity. These effects of lyoniol-A on the respiration and the rigidity were absent under conditions of bilateral cervical vagotomy, and the hypotension was abolished by sectioning of both vagal and carotid sinus nerves. These results suggest that the excitation by lyoniol-A of the afferent activities reflexly produces respiratory depression, hypotension and the relief of decerebrate rigidity.
关键词：decerebrate rigidity