文章基本信息

标题：Effects of 1-Menthol and dl-Camphor on the Penetration and Hydrolysis of Methyl Salicylate in Hairless Mouse Skin
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作者：Tadanori YANO ; Tohru KANETAKE ; Masaru SAITA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1991
卷号：14
期号：12
页码：663-669
DOI：10.1248/bpb1978.14.663
出版社：The Pharmaceutical Society of Japan
摘要：Plasters containing methyl salicylate with and without l-menthol and dl-camphor were prepared and topically applied on hairless mouse skin to investigated the effects of l-menthol and dlcamphor on the skin penetration and hydrolysis of methyl salicylate in the skin. The in vitro hydrolysis of methyl salicylate was also investigated using the skin homogenate. It was found that l-menthol with dl-camphor enhanced the skin penetration of methyl salicylate, and they inhibited both the in vivo and in vitro hydrolysis of methyl salicylate to salicylic acid.
关键词：hairless mouse