文章基本信息

标题：CHARACTERIZATION OF MUTAGENIC PRINCIPLES AND CARCINOGENICITY TEST OF DILL WEED AND SEEDS
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作者：MASAMICHI FUKUOKA ; KUNITOSHI YOSHIHIRA ; SHINSAKU NATORI 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1980
卷号：3
期号：5
页码：236-244
DOI：10.1248/bpb1978.3.236
出版社：The Pharmaceutical Society of Japan
摘要：Among the various kinds of spices tested, the aqueous extracts of dill weed from Anethum graveolens L. and dill seeds from A. sowa D.C. (Umbelliferae), exhibited a mutagenicity to Salmonella typhimurium, strains TA98 and TA100. The aqueous methanol extracts were fractionated by the mutation assay using the strain TA98 with S-9 Mix. Isorhamnetin 3-sulfate (persicarin) and quercetin 3-sulfate were characterized as the mutagenic principles. Carcinogenicity was not observed for dill weed and seeds when the diets containing these in 33% were administered for 450 and 410 days, respectively, to the inbred strain ACI rats.
关键词：carcinogenicity test