文章基本信息

标题：BILAYER MEMBRANE FORMATION IN THE CHENODEOXYCHOLATE, PHOSPHATIDYLCHOLINE AND CHOLESTEROL SOLUTION
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作者：HIROTSUNE IGIMI ; KUNIHIKO MURATA
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1983
卷号：6
期号：4
页码：261-266
DOI：10.1248/bpb1978.6.261
出版社：The Pharmaceutical Society of Japan
摘要：The physicochemical process whereby bilayer membranes are formed in the chenodeoxycholate, phosphatidylcholine and cholesterol solution is described. Observations were made by electron microscopy using both the negative stain method and the freeze fracture method after excess amounts of cholesterol monohydrate crystals were incubated at varying ratios in sodium taurochenodeoxycholate and phosphatidylcholine solutions. A hypothesis of the transformational processes from bilayer disk to multilamellar liposome in the artificial bile is presented.
关键词：phosphatidylcholine